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Purdue linebacker Jalen Graham (6) tackles Iowa quarterback Spencer Petras (7) during the second half of an NCAA college football game, Saturday, Oct. 16, 2021, in Iowa City, Iowa. Purdue won 24-7. (AP Photo/Charlie Neibergall)

Boilermakers using creative combination to rejoin Top 25

Purdue coach Jeff Brohm spent his bye week designing a creative game plan, capable of pulling off one of this season's biggest upsets.

Arizona quarterback Gunner Cruz, top, jumps over Colorado defensive lineman Justin Jackson in the second half of an NCAA college football game Saturday, Oct. 16, 2021, in Boulder, Colo. (AP Photo/David Zalubowski)

Arizona QB Cruz out for rest of season with thumb injury

TUCSON, Ariz. (AP) — Arizona has lost its second quarterback in two weeks to a season-ending injury.

Alabama defensive back Jordan Battle (9) celebrates his interception of a Mississippi State pass during the second half of an NCAA college football game in Starkville, Miss., Saturday, Oct. 16, 2021. Alabama won 49-9. (AP Photo/Rogelio V. Solis)

AP Top 25 Reality Check: Blue bloods chasing No. 2 Bearcats

A look at the top of The Associated Press college football poll might produce this reaction: One of these things is not like the other.