Kansas (3-7, 1-6 Big 12) at No. 6 Oklahoma (9-1, 6-1, No. 6 CFP), 7:30 p.m. EST (FOX).
Line: Oklahoma by 36.
Series record: Oklahoma leads 75-27-6.
WHAT'S AT STAKE?
Oklahoma is trying to remain in the running for a spot in the Big 12 title game and a shot at the College Football Playoff, and QB Kyler Murray is trying to strengthen his case for the Heisman Trophy. Kansas has a chance to get a big win for coach David Beaty, who will not be retained after the season.
Oklahoma QB Kyler Murray vs. Kansas defense. Murray has posted what projects to be the most efficient passing season in FBS history while rushing for 640 yards. Kansas is ninth in the Big 12 in total defense.
PLAYERS TO WATCH
Kansas: RB Pooka Williams. The freshman is sixth in the Big 12 with 68.9 yards per game in league play and second in all-purpose yardage with 133.9 yards per game.
Oklahoma: RBs Kennedy Brooks and Trey Sermon. Brooks, a freshman, is averaging 98.2 yards per game and 11.1 yards per carry in league play. Sermon is averaging 92.1 yards per game in conference play. Together, they have helped the Sooners lead the Big 12 in rushing by a wide margin.
FACTS & FIGURES
Oklahoma has won 15 straight November games dating back to 2014. ... Oklahoma has won 13 straight in the series. ... Kansas LB Joe Dineen leads the Big 12 in tackles. ... Oklahoma WR Marquise Brown is a semifinalist for the Biletnikoff Award for the nation's top receiver. ... Oklahoma OG Ben Powers is a semifinalist for the Outland Trophy, which is awarded to the nation's best interior offensive or defensive lineman.
More AP college football: http://collegefootball.ap.org and http://www.twitter.com/AP_Top25 .